Batman Universitesi Yasam Bilimleri Dergisi
Cilt 5, Sayı 1  Ocak-Haziran 2015  (ISSN: 2147-4877, E-ISSN: 2459-0614)

NO Makale Adı
1431430237 A Review on Calculation Binding Kass from NMR Data

Chirality studies at molecular level have started to become the most fundametal subject of modern chemistry. An important reason for wide interest in this field is chiral nature of most biomolecules and interaction of these molecules with the others. Most medicinal drugs and agricultural chemicals contain chiral molecules. While asymmetric synthesis has developed greatly in recent years, this method has not introduced a practical technique for preparing most of pure chiral compounds yet. A great deal of materials have been synthesized to understand completely factors effecting chiral recognition at molecular level. Knowledge gained through studying supramolecular chemistry by this respect has further importance since it enable to understand the factors that have impact on biological recognition events such as enzyme-substrate and antibody-antigen interactions. On the otherhand, enantiomeric recognition studies of chiral amine and protonated chiral amine are also important since these compounds are building blocks of biological molecules. The most widely used compounds for this purpose in supramolecular chemistry are chiral crown eters, cyclodextrins and cyclophanes.